HNRNPK 抗体 (pSer216)
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Quick Overview for HNRNPK 抗体 (pSer216) (ABIN7221532)
抗原
See all HNRNPK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer216
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原理
- hnRNP K (phospho Ser216) Polyclonal Antibody
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特异性
- Phospho-hnRNP K (S216) Polyclonal Antibody detects endogenous levels of hnRNP K protein only when phosphorylated at S216.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human hnRNP K Phospho-Ser216
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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别名
- hnRNP K
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背景
- Rabbit Anti-hnRNP K (phospho Ser216) Polyclonal Antibody,HNRNPK, HNRPK, Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP,HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.,Heterogeneous nuclear ribonucleoprotein K
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分子量
- observerd band 55kDa
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基因ID
- 3190
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UniProt
- P61978
抗原
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