H2AFZ 抗体 (AA 1-30)
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Quick Overview for H2AFZ 抗体 (AA 1-30) (ABIN7227046)
抗原
See all H2AFZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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原理
- Histone H2A.Z Polyclonal Antibody
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特异性
- The antibody detects endogenous Histone H2A.Z.
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthetic peptide from human protein at AA range: 1-30
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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别名
- Histone H2A.Z
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背景
- Rabbit Anti-Histone H2A.Z Polyclonal Antibody,Histone H2A.Z, H2A/z,Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFZ (H2A histone family member Z) encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.,Histone H2A.Z
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分子量
- observerd band 20kDa
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基因ID
- 3015
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UniProt
- P0C0S5
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途径
- Telomere Maintenance
抗原
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