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GZMB 抗体

This 兔 多克隆 anti-GZMB antibody specifically detects GZMB in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7228772
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GZMB 抗体 (ABIN7228772)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

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人, 小鼠, 大鼠

宿主

  • 99
  • 82
  • 2

克隆类型

  • 101
  • 82
多克隆

标记

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This GZMB antibody is un-conjugated

应用范围

  • 85
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Western Blotting (WB), ELISA
  • 原理

    Granzyme B Polyclonal Antibody

    特异性

    This antibody detects endogenous levels of Granzyme B.

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human Granzyme B protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B

    背景

    Rabbit Anti-Granzyme B Polyclonal Antibody,Granzyme B, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E,GZMB encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of GZMB may be elevated in human patients with cardiac fibrosis.,Granzyme B

    分子量

    observerd band 40kDa

    基因ID

    3002

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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