GP6 抗体
Our Local Distributor
北京 101111
Quick Overview for GP6 抗体 (ABIN7228766)
抗原
See all GP6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-GPVI Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of GPVI protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human GPVI protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- GP6 (Glycoprotein VI (Platelet) (GP6))
-
别名
- GPVI
-
背景
- Platelet glycoprotein VI, GPVI, Glycoprotein 6GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. Glycoprotein VI Platelet is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
-
分子量
- 55kD
-
基因ID
- 51206
-
UniProt
- Q9HCN6
抗原
-