GP6 抗体 (C-Term)
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- 抗原 See all GP6 抗体
- GP6 (Glycoprotein VI (Platelet) (GP6))
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抗原表位
- AA 309-337, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GP6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This GP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human GP6.
- 克隆位点
- RB22884
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GP6 Primary Antibody
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anti-Glycoprotein VI (Platelet) (GP6) (AA 86-231) antibody
GP6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein VI (Platelet) (GP6) (AA 115-265) antibodyGP6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein VI (Platelet) (GP6) (C-Term) antibodyGP6 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:100. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- GP6 (Glycoprotein VI (Platelet) (GP6))
- 别名
- GP6 (GP6 产品)
- 别名
- BDPLT11 antibody, GPIV antibody, GPVI antibody, 9830166G18Rik antibody, Gm469 antibody, Gpvi antibody, GP6 antibody, glycoprotein VI platelet antibody, glycoprotein 6 (platelet) antibody, glycoprotein VI antibody, platelet glycoprotein VI antibody, GP6 antibody, Gp6 antibody, LOC103346235 antibody
- 背景
- Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss. However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke (Jandrot-Perrus et al., 2000 [PubMed 10961879]).
- 分子量
- 36866
- 基因ID
- 51206
- NCBI登录号
- NP_001242946, NP_057447
- UniProt
- Q9HCN6
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