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Glutamate Receptor 1 抗体 (pSer849)

This 兔 多克隆 antibody specifically detects Glutamate Receptor 1 in ELISA 和 IHC (p). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7221296
发货至: 中国
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Quick Overview for Glutamate Receptor 1 抗体 (pSer849) (ABIN7221296)

抗原

See all Glutamate Receptor 1 (GLUR1) 抗体
Glutamate Receptor 1 (GLUR1)

适用

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人, 大鼠, 小鼠

宿主

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  • 1
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克隆类型

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多克隆

标记

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This Glutamate Receptor 1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer849

    原理

    GluR-1 (phospho Ser849) Polyclonal Antibody

    特异性

    Phospho-GluR-1 (S849) Polyclonal Antibody detects endogenous levels of GluR-1 protein only when phosphorylated at S849.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human GluR-1 Phospho-Ser849

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Glutamate Receptor 1 (GLUR1)

    别名

    GluR-1

    背景

    Rabbit Anti-GluR-1 (phospho Ser849) Polyclonal Antibody,GRIA1, GLUH1, GLUR1, Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1,Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,Glutamate receptor 1

    基因ID

    2890

    UniProt

    P42261

    途径

    PI3K-Akt Signaling
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