GLI2 抗体
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北京 101111
Quick Overview for GLI2 抗体 (ABIN7228666)
抗原
See all GLI2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GLI2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of GLI2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human GLI2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GLI2 (GLI Family Zinc Finger 2 (GLI2))
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别名
- GLI2
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背景
- Rabbit Anti-GLI2 Polyclonal Antibody,Zinc finger protein GLI2, GLI family zinc finger protein 2, Tax helper protein,GLI2 gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.,GLI2
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分子量
- observerd band 174kDa
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基因ID
- 2736
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UniProt
- P10070
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途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
抗原
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