GFRA2 抗体 (AA 320-400)
Quick Overview for GFRA2 抗体 (AA 320-400) (ABIN7228652)
抗原
See all GFRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 320-400
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原理
- GFRA2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of GFRA2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human GFRA2 protein at AA range: 320-400
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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别名
- GFRA2
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背景
- Rabbit Anti-GFRA2 Polyclonal Antibody,GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2,Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. GFRA2 is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for GFRA2.,GFRA2
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分子量
- observerd band 51kDa
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基因ID
- 2675
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UniProt
- O00451
抗原
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