GPBAR1 抗体 (AA 30-110)
Quick Overview for GPBAR1 抗体 (AA 30-110) (ABIN7219850)
抗原
See all GPBAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- TGR5 Polyclonal Antibody
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特异性
- TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human TGR5 at AA range: 30-110
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
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别名
- TGR5
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背景
- Rabbit Anti-TGR5 Polyclonal Antibody,GPBAR1, TGR5, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, hGPCR19, Membrane-type receptor for bile acids, M-BAR, hBG37, BG37,GPBAR1 encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.,G-protein coupled bile acid receptor 1
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基因ID
- 151306
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UniProt
- Q8TDU6
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途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
抗原
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