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GPBAR1 抗体 (AA 30-110)

This anti-GPBAR1 antibody is a 兔 多克隆 antibody detecting GPBAR1 in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7219850
发货至: 中国

Quick Overview for GPBAR1 抗体 (AA 30-110) (ABIN7219850)

抗原

See all GPBAR1 抗体
GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPBAR1 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 30-110

    原理

    TGR5 Polyclonal Antibody

    特异性

    TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human TGR5 at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

    别名

    TGR5

    背景

    Rabbit Anti-TGR5 Polyclonal Antibody,GPBAR1, TGR5, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, hGPCR19, Membrane-type receptor for bile acids, M-BAR, hBG37, BG37,GPBAR1 encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.,G-protein coupled bile acid receptor 1

    基因ID

    151306

    UniProt

    Q8TDU6

    途径

    WNT signaling, Hormone Transport, Sensory Perception of Sound
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