GFM2 抗体 (AA 410-490)
Quick Overview for GFM2 抗体 (AA 410-490) (ABIN7225406)
抗原
See all GFM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 410-490
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原理
- EF-G2 Polyclonal Antibody
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特异性
- EF-G2 Polyclonal Antibody detects endogenous levels of EF-G2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human EF-G2 at AA range: 410-490
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))
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别名
- EF-G2
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背景
- Rabbit Anti-EF-G2 Polyclonal Antibody,GFM2, EFG2, MSTP027, Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2, Elongation factor G2, hEFG2,Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 (G elongation factor mitochondrial 2) encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,Ribosome-releasing factor 2 mitochondrial
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分子量
- observerd band 87kDa
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基因ID
- 84340
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UniProt
- Q969S9
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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