GFM2 抗体 (AA 441-490)
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Quick Overview for GFM2 抗体 (AA 441-490) (ABIN1534880)
抗原
See all GFM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 441-490
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原理
- EF-G2 Antibody
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特异性
- EF-G2 Polyclonal Antibody detects endogenous levels of EF-G2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GFM2. AA range:441-490
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))
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别名
- GFM2
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背景
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Synonyms: GFM2, EFG2, MSTP027, Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2, Elongation factor G2, hEFG2
Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013],
Gene Name: GFM2
Protein Name: Ribosome-releasing factor 2 mitochondrial
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分子量
- 86 kDa
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基因ID
- 84340
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OMIM
- 606544
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UniProt
- Q969S9
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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