FZD8 抗体 (AA 460-540)
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Quick Overview for FZD8 抗体 (AA 460-540) (ABIN7225246)
抗原
See all FZD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 460-540
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原理
- Frizzled-8 Polyclonal Antibody
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特异性
- Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Frizzled-8 at AA range: 460-540
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FZD8 (Frizzled Family Receptor 8 (FZD8))
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别名
- Frizzled-8
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背景
- Rabbit Anti-Frizzled-8 Polyclonal Antibody,FZD8, Frizzled-8, Fz-8, hFz8,This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.,Frizzled-8
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分子量
- observerd band 70kDa
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基因ID
- 8325
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UniProt
- Q9H461
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途径
- WNT signaling
抗原
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