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FZD8 抗体 (AA 460-540)

This 兔 多克隆 anti-FZD8 antibody specifically detects FZD8 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7225246
发货至: 中国
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Quick Overview for FZD8 抗体 (AA 460-540) (ABIN7225246)

抗原

See all FZD8 抗体
FZD8 (Frizzled Family Receptor 8 (FZD8))

适用

  • 69
  • 56
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  • 5
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  • 2
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 66
  • 3
  • 2
  • 2

克隆类型

  • 53
  • 20
多克隆

标记

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  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FZD8 antibody is un-conjugated

应用范围

  • 48
  • 23
  • 17
  • 11
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  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 460-540

    原理

    Frizzled-8 Polyclonal Antibody

    特异性

    Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Frizzled-8 at AA range: 460-540

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FZD8 (Frizzled Family Receptor 8 (FZD8))

    别名

    Frizzled-8

    背景

    Rabbit Anti-Frizzled-8 Polyclonal Antibody,FZD8, Frizzled-8, Fz-8, hFz8,This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.,Frizzled-8

    分子量

    observerd band 70kDa

    基因ID

    8325

    UniProt

    Q9H461

    途径

    WNT signaling
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