FZD6 抗体 (AA 90-170)
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北京 101111
Quick Overview for FZD6 抗体 (AA 90-170) (ABIN7225244)
抗原
See all FZD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-170
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原理
- Frizzled-6 Polyclonal Antibody
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特异性
- Frizzled-6 Polyclonal Antibody detects endogenous levels of Frizzled-6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Frizzled-6 at AA range: 90-170
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亚型
- IgG
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anti-Frizzled Family Receptor 6 (FZD6) (C-Term) antibody
FZD6 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (N-Term) antibodyFZD6 适用: 人, 猴 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 11-110) antibodyFZD6 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) antibodyFZD6 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 19-201) antibodyFZD6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 539-588) antibodyFZD6 适用: 人, 大鼠, 猴, Cow, 犬, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 116-165) antibodyFZD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (Extracellular Domain), (N-Term) antibodyFZD6 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FZD6 (Frizzled Family Receptor 6 (FZD6))
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别名
- Frizzled-6
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背景
- Rabbit Anti-Frizzled-6 Polyclonal Antibody,FZD6, Frizzled-6, Fz-6, hFz6,FZD6 (frizzled class receptor 6) represents a member of the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.,Frizzled-6
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分子量
- observerd band 79kDa
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基因ID
- 8323
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UniProt
- O60353
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途径
- WNT signaling, Tube Formation
抗原
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