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FHIT 抗体 (pTyr114)

This anti-FHIT antibody is a 兔 多克隆 antibody detecting FHIT in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7220538
发货至: 中国

Quick Overview for FHIT 抗体 (pTyr114) (ABIN7220538)

抗原

See all FHIT 抗体
FHIT (Fragile Histidine Triad (FHIT))

适用

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宿主

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克隆类型

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多克隆

标记

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This FHIT antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr114

    原理

    Fhit (phospho Tyr114) Polyclonal Antibody

    特异性

    Phospho-Fhit (Y114) Polyclonal Antibody detects endogenous levels of Fhit protein only when phosphorylated at Y114.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Fhit Phospho-Tyr114

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FHIT (Fragile Histidine Triad (FHIT))

    别名

    Fhit

    背景

    Rabbit Anti-Fhit (phospho Tyr114) Polyclonal Antibody,FHIT, Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5', 5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein,FHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.,Bis(5'-adenosyl)-triphosphatase

    基因ID

    2272

    UniProt

    P49789
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