FHIT 抗体 (AA 1-147)
(2 references)-
- 抗原 See all FHIT 抗体
- FHIT (Fragile Histidine Triad (FHIT))
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抗原表位
- AA 1-147
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FHIT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Bis(5'-adenosyl)-triphosphatase(FHIT) detection. Tested with WB, IHC-P in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Bis(5'-adenosyl)-triphosphatase(FHIT) detection. Tested with WB, IHC-P in Human.
Gene Name: fragile histidine triad
Protein Name: Bis(5'-adenosyl)-triphosphatase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human FHIT recombinant protein (Position: M1-Q147). Human FHIT shares 90% and 87% amino acid (aa) sequences identity with mouse and rat FHIT, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product FHIT Primary Antibody
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anti-Fragile Histidine Triad (FHIT) (AA 25-147) antibody
FHIT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (Internal Region) antibodyFHIT 适用: 人, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) antibodyFHIT 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-147) antibodyFHIT 适用: 人 ELISA, WB, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 2-147) antibodyFHIT 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) antibodyFHIT 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1C5 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for FHIT is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia." in: International journal of molecular sciences, Vol. 11, Issue 11, pp. 4580-90, (2010) (PubMed).
: "Coxsackievirus B3: primary structure of the 5' non-coding and capsid protein-coding regions of the genome." in: Virus research, Vol. 3, Issue 3, pp. 263-70, (1986) (PubMed).
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: "Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia." in: International journal of molecular sciences, Vol. 11, Issue 11, pp. 4580-90, (2010) (PubMed).
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- 抗原
- FHIT (Fragile Histidine Triad (FHIT))
- 别名
- FHIT (FHIT 产品)
- 别名
- AP3Aase antibody, FRA3B antibody, FHIT antibody, zgc:73176 antibody, AW045638 antibody, Fra14A2 antibody, LOC100223655 antibody, fragile histidine triad antibody, fragile histidine triad gene antibody, fragile histidine triad protein antibody, fragile histidine triad L homeolog antibody, FHIT antibody, Fhit antibody, fhit antibody, PY07476 antibody, fhit.L antibody
- 背景
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Bis(5'-adenosyl)-triphosphatase, also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene. This gene, a member of the histidine triad gene family, encodes a diadenosine P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3p14.2, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Furthermore, FHIT has been shown to synergize with VHL, another tumor suppressor, in protecting against chemically - induced lung cancer. It also acts as a tumor suppressor of HER2/neu driven breast cancer.
Synonyms: AP3A hydrolase antibody|AP3A hydrolase fragile site 3p14.2 antibody|AP3Aase antibody|Bis 5' adenosyl triphosphatase antibody|Bis(5' adenosyl) triphosphatase antibody|Diadenosine 5' 5''' P1 P3 triphosphate hydrolase antibody|Dinucleosidetriphosphatase antibody|FRA 3B antibody|FRA3B antibody|Fragile histidine triad antibody|Fragile histidine triad gene antibody|Fragile histidine triad protein antibody|Tumor suppressor protein antibody - 基因ID
- 2272
- UniProt
- P49789
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