FRS2 抗体
Our Local Distributor
北京 101111
Quick Overview for FRS2 抗体 (ABIN7214962)
抗原
See all FRS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- FRS2 Polyclonal Antibody
-
特异性
- FRS2 Polyclonal Antibody detects endogenous levels of FRS2 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human FRS2 around the non-phosphorylation site of Y196
-
亚型
- IgG
-
-
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Tyr580) antibody
FRS2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 239-449) antibodyFRS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Tyr196) antibodyFRS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) antibodyFRS2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5785 unconjugated Recombinant Antibody
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 1-341) antibodyFRS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7-1D6 unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 268-453) antibodyFRS2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 268-453) antibodyFRS2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 402-451), (pTyr436) antibodyFRS2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
-
别名
- FRS2
-
背景
- Rabbit Anti-FRS2 Polyclonal Antibody,FRS2, Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1,FRS2 is a gene on chromosome 12q15 that encodes an adapter protein which links activated FGR and NGF receptors to downstream signalling pathways. Fibroblast growth factor receptor substrate 2 plays a key role in activating MAP kinases and in phosphorylating PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Fibroblast growth factor receptor substrate 2 modulates signalling via SHC1 by competing with it for a common binding site on NTRK1. It is usually part of heteromultimeric protein complexes, and it is highly expressed in the heart, brain, spleen, lungs, liver, skeletal muscle, kidneys and testes.,Fibroblast growth factor receptor substrate 2
-
分子量
- observerd band 65kDa
-
基因ID
- 10818
-
UniProt
- Q8WU20
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
-
