FRS2 抗体 (pTyr436)
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北京 101111
Quick Overview for FRS2 抗体 (pTyr436) (ABIN7213282)
抗原
See all FRS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr436
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原理
- FRS2 (phospho Tyr436) Polyclonal Antibody
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特异性
- Phospho-FRS2 (Y436) Polyclonal Antibody detects endogenous levels of FRS2 protein only when phosphorylated at Y436.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human FRS2 Phospho-Tyr436
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亚型
- IgG
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anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Tyr580) antibody
FRS2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 239-449) antibodyFRS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Tyr196) antibodyFRS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) antibodyFRS2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5785 unconjugated Recombinant Antibody
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 1-341) antibodyFRS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7-1D6 unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 268-453) antibodyFRS2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 268-453) antibodyFRS2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 402-451), (pTyr436) antibodyFRS2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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别名
- FRS2
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背景
- Rabbit Anti-FRS2 (phospho Tyr436) Polyclonal Antibody,FRS2, Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1,Fibroblast growth factor (FGF) receptor substrate 2 (FRS2) has an alternative name as SNT-1, it is an adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. FGF receptor substrates (FRS2 and FRS3) are key adaptor proteins that mediate FGF-FGFR signalling in benign as well as malignant tissue. FRS2 is a 508 amino-acid protein, which is phosphorylated on tyrosine residues. The molecular weight of non-phosphorylated FRS2 is 57-68 kDa, but phosphorylated FRS2 is 80-90 kDa. Phosphorylation of FRS2 is associated with activation of a number of MAP kinases. Allele-specific regulation of FGFR2 mRNA expression with a mildly increased breast cancer risk has been reported.,Fibroblast growth factor receptor substrate 2
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分子量
- observerd band 65kDa
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基因ID
- 10818
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UniProt
- Q8WU20
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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