FAT1 抗体 (AA 1140-1220)
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Quick Overview for FAT1 抗体 (AA 1140-1220) (ABIN7228488)
抗原
See all FAT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1140-1220
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原理
- FAT1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of FAT1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human FAT1 protein at AA range: 1140-1220
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))
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别名
- FAT1
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背景
- Rabbit Anti-FAT1 Polyclonal Antibody,Protocadherin Fat 1, Cadherin family member 7, Cadherin-related tumor suppressor homolog, Protein fat homolog, Protocadherin Fat 1, nuclear form,FAT1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. FAT1 product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, FAT1 product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. FAT1 is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.,FAT1
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分子量
- observerd band 504kDa
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基因ID
- 2195
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UniProt
- Q14517
抗原
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