FANCM 抗体
Quick Overview for FANCM 抗体 (ABIN7228482)
抗原
See all FANCM 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FANCM Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of FANCM protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human FANCM protein
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亚型
- IgG
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anti-Fanconi Anemia Complementation Group M (FANCM) (Internal Region) antibody
FANCM 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group M (FANCM) (AA 1-669) antibodyFANCM 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group M (FANCM) (AA 1752-1783) antibodyFANCM 适用: 人 WB 宿主: 兔 Polyclonal RB54125 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FANCM (Fanconi Anemia Complementation Group M (FANCM))
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别名
- FANCM
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背景
- Rabbit Anti-FANCM Polyclonal Antibody,Fanconi anemia group M protein, Protein FACM, ATP-dependent RNA helicase FANCM Fanconi anemia-associated polypeptide of 250 kDa, FAAP250, Protein Hef ortholog,The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants. FANCM (Fanconi Anemia Complementation Group M) is a Protein Coding gene. Diseases associated with FANCM include Fanconi Anemia, Complementation Group A and Fancm-Related Fanconi Anemia. Among its related pathways are Fanconi anemia pathway and DNA Double-Strand Break Repair.,FANCM
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分子量
- observerd band 225kDa
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基因ID
- 57697
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UniProt
- Q8IYD8
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途径
- DNA Damage Repair
抗原
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