Factor VII 抗体 (Cleaved-Arg212)
Our Local Distributor
北京 101111
Quick Overview for Factor VII 抗体 (Cleaved-Arg212) (ABIN7212512)
抗原
See all Factor VII (F7) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 140-220, Cleaved-Arg212
-
原理
- Rabbit Anti-Cleaved-Factor VII LC (R212) Polyclonal Antibody
-
特异性
- Cleaved-Factor VII LC (R212) Polyclonal Antibody detects endogenous levels of fragment of activated Factor VII LC protein resulting from cleavage adjacent to R212.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from the Internal region of human Factor VII LC at AA range: 140-220
-
亚型
- IgG
-
-
anti-Coagulation Factor VII (F7) (AA 42-169) antibody
F7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (Internal Region) antibodyF7 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 IHC, ELISA, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 302-332) antibodyF7 适用: 人 WB 宿主: 兔 Polyclonal RB54990 unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 WB, ELISA, RIA 宿主: 小鼠 Monoclonal RFF-VII-1 unconjugated
anti-Coagulation Factor VII (F7) (AA 251-300) antibodyF7 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 173-222) antibodyF7 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- Factor VII (F7) (Coagulation Factor VII (F7))
-
别名
- Factor VII LC
-
背景
- F7, Coagulation factor VII, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfaF7 encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
-
分子量
- 17kD
-
基因ID
- 2155
-
UniProt
- P08709
-
途径
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
抗原
-
