ERCC1 抗体 (AA 110-190)
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北京 101111
Quick Overview for ERCC1 抗体 (AA 110-190) (ABIN7220352)
抗原
See all ERCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-190
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原理
- ERCC1 Polyclonal Antibody
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特异性
- ERCC1 Polyclonal Antibody detects endogenous levels of ERCC1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human ERCC1 at AA range: 110-190
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亚型
- IgG
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anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 151-250) antibody
ERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-297) antibodyERCC1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5A2D1 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) antibodyKD Validated ERCC1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB1230 unconjugated Recombinant Antibody
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 191-281) antibodyERCC1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ERCC1-2318 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 151-297) antibodyERCC1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1E5B3 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-120) antibodyERCC1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F9E9 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-323) antibodyERCC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-323) antibodyERCC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (Internal Region) antibodyERCC1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (Internal Region) antibodyERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
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别名
- ERCC1
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背景
- Rabbit Anti-ERCC1 Polyclonal Antibody,ERCC1, DNA excision repair protein ERCC-1,The product of ERCC1 functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of ERCC1 may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.,DNA excision repair protein ERCC-1
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分子量
- observerd band 36kDa
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基因ID
- 2067
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UniProt
- P07992
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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