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Ephrin B3 抗体 (AA 190-270)

This anti-Ephrin B3 antibody is a 兔 多克隆 antibody detecting Ephrin B3 in ELISA, WB 和 IHC (p). Suitable for 小鼠, 人 和 大鼠.
产品编号 ABIN7220132
发货至: 中国
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Quick Overview for Ephrin B3 抗体 (AA 190-270) (ABIN7220132)

抗原

See all Ephrin B3 (EFNB3) 抗体
Ephrin B3 (EFNB3)

适用

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小鼠, 人, 大鼠

宿主

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克隆类型

  • 39
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多克隆

标记

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This Ephrin B3 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 190-270

    原理

    Ephrin-B3 Polyclonal Antibody

    特异性

    Ephrin-B3 Polyclonal Antibody detects endogenous levels of Ephrin-B3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Ephrin-B3 at AA range: 190-270

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Ephrin B3 (EFNB3)

    别名

    Ephrin-B3

    背景

    Rabbit Anti-Ephrin-B3 Polyclonal Antibody,EFNB3, EPLG8, LERK8, Ephrin-B3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, LERK-8,EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.,Ephrin-B3

    分子量

    observerd band 36kDa

    基因ID

    1949

    UniProt

    Q15768

    途径

    RTK signaling
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