NEIL2 抗体
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北京 101111
Quick Overview for NEIL2 抗体 (ABIN7229952)
抗原
See all NEIL2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NEIL2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of NEIL2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human NEIL2 protein
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亚型
- IgG
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anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibody
NEIL2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Endonuclease 8-like 2 (NEIL2) (Internal Region) antibodyNEIL2 适用: 人, 小鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibodyNEIL2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease 8-like 2 (NEIL2) antibodyNEIL2 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2626C2a unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NEIL2 (Endonuclease 8-like 2 (NEIL2))
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别名
- NEIL2
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背景
- Rabbit Anti-NEIL2 Polyclonal Antibody,Endonuclease 8-like 2, DNA glycosylase/AP lyase Neil2, DNA-(apurinic or apyrimidinic site) lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein 2,NEIL2 encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified.,NEIL2
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分子量
- observerd band 36kDa
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基因ID
- 252969
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UniProt
- Q969S2
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途径
- DNA Damage Repair
抗原
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