Endoglin 抗体 (AA 370-430)
Quick Overview for Endoglin 抗体 (AA 370-430) (ABIN7228398)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-430
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原理
- Endoglin Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of Endoglin
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human Endoglin protein at AA range: 370-430
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Endoglin (ENG)
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别名
- Endoglin
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背景
- Rabbit Anti-Endoglin Polyclonal Antibody,Endoglin, CD antigen CD105,Endoglin encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in Endoglin cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Endoglin may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for Endoglin.,Endoglin
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分子量
- observerd band 70kDa
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基因ID
- 2022
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UniProt
- P17813
抗原
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