DKC1 抗体 (AA 140-220)
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Quick Overview for DKC1 抗体 (AA 140-220) (ABIN7220050)
抗原
See all DKC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-220
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原理
- Dyskerin Polyclonal Antibody
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特异性
- Dyskerin Polyclonal Antibody detects endogenous levels of Dyskerin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Dyskerin at AA range: 140-220
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亚型
- IgG
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anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) antibody
DKC1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 1-180) antibodyDKC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) antibodyDKC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 1-514) antibodyDKC1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 1-514) antibodyDKC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 94-170) antibodyDKC1 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) antibodyDKC1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1810 unconjugated Recombinant Antibody
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 298-465) antibodyDKC1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 298-509) antibodyDKC1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 185-213) antibodyDKC1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB26907 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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别名
- Dyskerin
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背景
- Rabbit Anti-Dyskerin Polyclonal Antibody,DKC1, NOLA4, H/ACA ribonucleoprotein complex subunit 4, CBF5 homolog, Dyskerin, Nopp140-associated protein of 57 kDa, Nucleolar protein NAP57, Nucleolar protein family A member 4, snoRNP protein DKC1,Dihydroorotate dehydrogenase encoded by DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. DKC1 functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.,H
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分子量
- observerd band 57kDa
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基因ID
- 1736
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UniProt
- O60832
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途径
- Telomere Maintenance
抗原
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