DUSP6 抗体 (AA 30-110)
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Quick Overview for DUSP6 抗体 (AA 30-110) (ABIN7220100)
抗原
See all DUSP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- Rabbit Anti-MKP-3 Polyclonal Antibody
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特异性
- MKP-3 Polyclonal Antibody detects endogenous levels of MKP-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human MKP-3 at AA range: 30-110
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亚型
- IgG
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anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 1-381) antibody
DUSP6 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 1-300) antibodyDUSP6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 58-89) antibodyDUSP6 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB05814 unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 1-170) antibodyDUSP6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 59-88) antibodyDUSP6 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) antibodyDUSP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 100-206) antibodyDUSP6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (AA 1-382) antibodyDUSP6 适用: 人 WB, ELISA, IHC, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (Internal Region) antibodyDUSP6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 6 (DUSP6) (C-Term) antibodyDUSP6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
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别名
- MKP-3
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背景
- DUSP6, MKP3, PYST1, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3The dual specificity phosphatase 6 encoded by DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 42kD
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基因ID
- 1848
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UniProt
- Q16828
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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