DR4 抗体 (AA 370-450)
Quick Overview for DR4 抗体 (AA 370-450) (ABIN7214618)
抗原
See all DR4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 370-450
-
原理
- DR4 Polyclonal Antibody
-
特异性
- DR4 Polyclonal Antibody detects endogenous levels of DR4 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human DR4 at AA range: 370-450
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- DR4 (Drought-Repressed 4 Protein (DR4))
-
别名
- DR4
-
背景
- Rabbit Anti-DR4 Polyclonal Antibody,TNFRSF10A, APO2, DR4, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, CD antigen CD261,TNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.,Tumor necrosis factor receptor superfamily member 10A
-
分子量
- observerd band 50kDa
-
基因ID
- 8797
-
UniProt
- O00220
-
途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
-