DOK2 抗体 (pTyr345)
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Quick Overview for DOK2 抗体 (pTyr345) (ABIN7225782)
抗原
See all DOK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr345
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原理
- Dok-2 (phospho Tyr345) Polyclonal Antibody
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特异性
- Phospho-Dok-2 (Y345) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y345.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Dok-2 Phospho-Tyr345
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DOK2
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别名
- Dok-2
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背景
- Rabbit Anti-Dok-2 (phospho Tyr345) Polyclonal Antibody,DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2),The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.,Docking protein 2
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基因ID
- 9046
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UniProt
- O60496
抗原
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