DOK4 抗体 (AA 30-110)
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北京 101111
Quick Overview for DOK4 抗体 (AA 30-110) (ABIN7214608)
抗原
See all DOK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- Dok-4 Polyclonal Antibody
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特异性
- Dok-4 Polyclonal Antibody detects endogenous levels of Dok-4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Dok-4 at AA range: 30-110
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亚型
- IgG
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anti-Docking Protein 4 (DOK4) (AA 240-326) antibody
DOK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) antibodyDOK4 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (AA 228-258), (C-Term) antibodyDOK4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1779-1780 unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (AA 11-60) antibodyDOK4 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (AA 38-87) antibodyDOK4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (C-Term) antibodyDOK4 适用: 人, 大鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DOK4 (Docking Protein 4 (DOK4))
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别名
- Dok-4
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背景
- Rabbit Anti-Dok-4 Polyclonal Antibody,DOK4, Docking protein 4, Downstream of tyrosine kinase 4, Insulin receptor substrate 5, IRS-5, IRS5,The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and, via this interaction, mediate biological responses within the body. Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.,Docking protein 4
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分子量
- observerd band 37kDa
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基因ID
- 55715
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UniProt
- Q8TEW6
抗原
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