DOK3 抗体 (AA 70-150)
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Quick Overview for DOK3 抗体 (AA 70-150) (ABIN7214606)
抗原
See all DOK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-150
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原理
- Dok-3 Polyclonal Antibody
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特异性
- Dok-3 Polyclonal Antibody detects endogenous levels of Dok-3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Dok-3 at AA range: 70-150
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亚型
- IgG
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anti-Docking Protein 3 (DOK3) (AA 128-385) antibody
DOK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (C-Term) antibodyVerified DOK3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (AA 1-146) antibodyDOK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (Internal Region) antibodyDOK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) antibodyDOK3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB8360 unconjugated
anti-Docking Protein 3 (DOK3) antibodyDOK3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB8365 unconjugated
anti-Docking Protein 3 (DOK3) (AA 1-330) antibodyDOK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (AA 45-310) antibodyDOK3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) antibodyDOK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (C-Term) antibodyDOK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DOK3 (Docking Protein 3 (DOK3))
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别名
- Dok-3
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背景
- Rabbit Anti-Dok-3 Polyclonal Antibody,DOK3, Docking protein 3, Downstream of tyrosine kinase 3,Dok-1, Dok-2 and Dok-3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok-1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok-2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr-Abl. Dok-3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B cells and macrophages. Immunoreceptor-mediated cellular activation induces tyrosine phosphorylation of Dok-3. Upon phosphorylation, Dok-3 binds to 5' inositol phosphatase SHIP and the protein tyrosine kinase Csk. Dok-3 may play a significant role in the negative regulation of immunoreceptor signaling in hemopoietic cells.,Docking protein 3
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分子量
- observerd band 58kDa
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基因ID
- 79930
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UniProt
- Q7L591
抗原
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