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DOK3 抗体

DOK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7249172
发货至: 中国
  • 抗原 See all DOK3 抗体
    DOK3 (Docking Protein 3 (DOK3))
    适用
    • 41
    • 23
    • 3
    宿主
    • 54
    • 3
    • 1
    克隆类型
    • 57
    • 1
    多克隆
    标记
    • 24
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    This DOK3 antibody is un-conjugated
    应用范围
    • 48
    • 27
    • 20
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    • 7
    • 5
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    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human DOK3
    亚型
    IgG
    Top Product
    Discover our top product DOK3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, ELISA 1:1000-1:5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DOK3 (Docking Protein 3 (DOK3))
    别名
    DOK3 (DOK3 产品)
    别名
    DOK3 antibody, DOKL antibody, AI450713 antibody, Dokl antibody, docking protein 3 antibody, DOK3 antibody, Dok3 antibody
    背景
    DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 53 kDa

    UniProt
    Q7L591
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