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DDIT3 抗体

This anti-DDIT3 antibody is a 小鼠 单克隆 antibody detecting DDIT3 in WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7212278
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDIT3 抗体 (ABIN7212278)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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人, 小鼠, 大鼠

宿主

  • 142
  • 13
小鼠

克隆类型

  • 111
  • 44
单克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2B1
  • 原理

    CHOP Mouse Monoclonal Antibody (2B1)

    特异性

    CHOP protein detects endogenous levels of DDIT3.

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Synthetic Peptide of CHOP at AA range of 10-90

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:100-1:200).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    CHOP

    背景

    Mouse Anti-CHOP Mouse Monoclonal Antibody (2B1),DDIT3,DDIT3 (DNA damage inducible transcript 3) encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of DDIT3 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.,DDIT3

    分子量

    observerd band 27kDa

    基因ID

    1649

    UniProt

    P35638

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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