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ERCC5 抗体 (AA 100-180)

This anti-ERCC5 antibody is a 兔 多克隆 antibody detecting ERCC5 in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN7217516
发货至: 中国

Quick Overview for ERCC5 抗体 (AA 100-180) (ABIN7217516)

抗原

See all ERCC5 抗体
ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

适用

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宿主

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克隆类型

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多克隆

标记

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This ERCC5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 100-180

    原理

    XPG Polyclonal Antibody

    特异性

    XPG Polyclonal Antibody detects endogenous levels of XPG protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human XPG at AA range: 100-180

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

    别名

    XPG

    背景

    Rabbit Anti-XPG Polyclonal Antibody,ERCC5, ERCM2, XPG, XPGC, DNA repair protein complementing XP-G cells, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein,ERCC5 encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. DNA repair protein complementing XP-G cells may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.,DNA repair protein complementing XP-G cells

    分子量

    observerd band 130kDa

    基因ID

    2073

    UniProt

    P28715

    途径

    DNA Damage Repair
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