DVL1 抗体
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北京 101111
Quick Overview for DVL1 抗体 (ABIN7228320)
抗原
See all DVL1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-DVL1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DVL1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human DVL1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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别名
- DVL1
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背景
- Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
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分子量
- 76kD
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基因ID
- 1855
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UniProt
- O14640
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途径
- WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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