Desmoglein 2 抗体 (AA 370-450)
Quick Overview for Desmoglein 2 抗体 (AA 370-450) (ABIN7220094)
抗原
See all Desmoglein 2 (DSG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-450
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原理
- Dsg2 Polyclonal Antibody
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特异性
- Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Dsg2 at AA range: 370-450
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Desmoglein 2 (DSG2)
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别名
- Dsg2
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背景
- Rabbit Anti-Dsg2 Polyclonal Antibody,DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC,DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.,Desmoglein-2
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分子量
- observerd band 140kDa
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基因ID
- 1829
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UniProt
- Q14126
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途径
- Cell-Cell Junction Organization
抗原
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