TdT 抗体 (AA 350-430)
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Quick Overview for TdT 抗体 (AA 350-430) (ABIN7220066)
抗原
See all TdT (DNTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-430
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原理
- TdT Polyclonal Antibody
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特异性
- TdT Polyclonal Antibody detects endogenous levels of TdT protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human TdT at AA range: 350-430
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- TdT
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背景
- Rabbit Anti-TdT Polyclonal Antibody,DNTT, TDT, DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase,DNTT is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.,DNA nucleotidylexotransferase
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分子量
- observerd band 60kDa
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基因ID
- 1791
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UniProt
- P04053
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途径
- DNA Damage Repair
抗原
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