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DHRS2 抗体 (AA 80-160)

The 兔 多克隆 anti-DHRS2 antibody (ABIN7214562) specifically detects DHRS2 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7214562
发货至: 中国
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Quick Overview for DHRS2 抗体 (AA 80-160) (ABIN7214562)

抗原

See all DHRS2 抗体
DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

适用

  • 42
  • 20
  • 18
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 1

克隆类型

  • 41
  • 1
多克隆

标记

  • 17
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DHRS2 antibody is un-conjugated

应用范围

  • 35
  • 13
  • 13
  • 13
  • 11
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-160

    原理

    DHRS2 Polyclonal Antibody

    特异性

    DHRS2 Polyclonal Antibody detects endogenous levels of DHRS2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human DHRS2 at AA range: 80-160

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

    别名

    DHRS2

    背景

    Rabbit Anti-DHRS2 Polyclonal Antibody,DHRS2, Dehydrogenase/reductase SDR family member 2, Dicarbonyl reductase HEP27, Protein D,DHRS2 (dehydrogenase/reductase (SDR family) member 2), also known as SDR25C1 or HEP27, is a 258 amino acid protein that localizes to the nucleus and belongs to the short-chain dehydrogenase/reductase (SDR) family. Functioning as an NADPH-dependent dicarbonyl reductase, DHRS2 is thought to inhibit cell replication by either converting cortisone in cortisol, or by catalyzing the oxidation of androgen and estrogen. The gene encoding DHRS2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.,Dehydrogenase

    分子量

    observerd band 27kDa

    基因ID

    10202

    UniProt

    Q13268

    途径

    C21-Steroid Hormone Metabolic Process
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