DIDO1 抗体 (AA 130-210)
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北京 101111
Quick Overview for DIDO1 抗体 (AA 130-210) (ABIN7214568)
抗原
See all DIDO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-210
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原理
- Rabbit Anti-Dio-1 Polyclonal Antibody
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特异性
- Dio-1 Polyclonal Antibody detects endogenous levels of Dio-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the N-terminal region of human Dio-1 at AA range: 130-210
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DIDO1 (Death Inducer-Obliterator 1 (DIDO1))
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别名
- Dio-1
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背景
- DIDO1, C20orf158, DATF1, KIAA0333, Death-inducer obliterator 1, DIO-1, hDido1, Death-associated transcription factor 1, DATF-1Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for DIDO1, encoding multiple isoforms.
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分子量
- 244kD
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基因ID
- 11083
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UniProt
- Q9BTC0
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途径
- Hormone Activity
抗原
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