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DDB2 抗体 (AA 260-340)

This 兔 多克隆 anti-DDB2 antibody specifically detects DDB2 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7228156
发货至: 中国
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Quick Overview for DDB2 抗体 (AA 260-340) (ABIN7228156)

抗原

See all DDB2 抗体
DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

适用

  • 54
  • 18
  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 54
  • 3

克隆类型

  • 32
  • 25
多克隆

标记

  • 30
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
This DDB2 antibody is un-conjugated

应用范围

  • 38
  • 17
  • 17
  • 17
  • 15
  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-340

    原理

    DDB2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of DDB2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human DDB2 protein at AA range: 260-340

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

    别名

    DDB2

    背景

    Rabbit Anti-DDB2 Polyclonal Antibody,DNA damage-binding protein 2, DDB p48 subunit, DDBb, Damage-specific DNA-binding protein 2, UV-damaged DNA-binding protein 2, UV-DDB 2,DDB2 encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.,DDB2

    分子量

    observerd band 46kDa

    基因ID

    1643

    UniProt

    Q92466

    途径

    DNA Damage Repair
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