Cyclin D2 抗体
Our Local Distributor
北京 101111
Quick Overview for Cyclin D2 抗体 (ABIN7225728)
抗原
See all Cyclin D2 (CCND2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Cyclin D2 Polyclonal Antibody
-
特异性
- Cyclin D2 Polyclonal Antibody detects endogenous levels of Cyclin D2 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human Cyclin D2 around the non-phosphorylation site of T280
-
亚型
- IgG
-
-
anti-Cyclin D2 (CCND2) (AA 161-288) antibody
CCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 47-267) antibodyCCND2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 68-278) antibodyCCND2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 215-285) antibodyCCND2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (C-Term) antibodyCCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (pThr280) antibodyCCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Cyclin D2 (CCND2)
-
别名
- Cyclin D2
-
背景
- Rabbit Anti-Cyclin D2 Polyclonal Antibody,CCND2, G1/S-specific cyclin-D2,The protein encoded by CCND2 (cyclin D2) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of CCND2 was observed in ovarian and testicular tumors. Mutations in CCND2 are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3).,cyclin-D2
-
分子量
- observerd band 42kDa
-
基因ID
- 894
-
UniProt
- P30279
-
途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
-
