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DMP1 抗体 (AA 430-510)

This 兔 多克隆 anti-DMP1 antibody specifically detects DMP1 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7228256
发货至: 中国
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Quick Overview for DMP1 抗体 (AA 430-510) (ABIN7228256)

抗原

See all DMP1 (DMTF1) 抗体
DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This DMP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 430-510

    原理

    DMP1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of DMP1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human DMP1 protein at AA range: 430-510

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

    别名

    DMP1

    背景

    Rabbit Anti-DMP1 Polyclonal Antibody,Dentin matrix acidic phosphoprotein 1, DMP-1, Dentin matrix protein 1,Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. DMP1 structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for DMP1.,DMP1

    分子量

    observerd band 56kDa

    基因ID

    1758

    UniProt

    Q13316
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