DMP1 抗体 (C-Term)
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北京 101111
Quick Overview for DMP1 抗体 (C-Term) (ABIN2775903)
抗原
See all DMP1 (DMTF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- DMTF1 Antibody - C-terminal region
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序列
- SFNDAHVSKF SDQNSTELMN SVMVRTEEEI SDTDLKQEES PSDLASAYVT
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预测反应
- Dog: 92%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against DMTF1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DMTF1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34602-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Tooth Germ-Like Construct Transplantation for Whole-Tooth Regeneration: An In Vivo Study in the Miniature Pig." in: Artificial organs, Vol. 40, Issue 4, pp. E39-50, (2016) (PubMed).
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- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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别名
- DMTF1
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背景
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Background Information: This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 35 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: cyclin D binding myb like transcription factor 1
Alternative Symbols: DMP1, DMTF, MRUL, hDMP1
Protein Name: cyclin-D-binding Myb-like transcription factor 1
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分子量
- 54kDa
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基因ID
- 9988
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UniProt
- Q9Y222
抗原
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