COX11 抗体 (AA 30-110)
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Quick Overview for COX11 抗体 (AA 30-110) (ABIN7219602)
抗原
See all COX11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- COX11 Polyclonal Antibody
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特异性
- COX11 Polyclonal Antibody detects endogenous levels of COX11 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human COX11 at AA range: 30-110
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))
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别名
- COX11
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背景
- Rabbit Anti-COX11 Polyclonal Antibody,COX11, Cytochrome c oxidase assembly protein COX11, mitochondrial,Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX11 encodes COX11, cytochrome c oxidase copper chaperone which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.,Cytochrome c oxidase assembly protein COX11 mitochondrial
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分子量
- observerd band 31kDa
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基因ID
- 1353
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UniProt
- Q9Y6N1
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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