C5AR1 抗体
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北京 101111
Quick Overview for C5AR1 抗体 (ABIN7214086)
抗原
See all C5AR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CD88 Polyclonal Antibody
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特异性
- CD88 Polyclonal Antibody detects endogenous levels of CD88 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human CD88 around the non-phosphorylation site of S338
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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别名
- CD88
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背景
- Rabbit Anti-CD88 Polyclonal Antibody,C5AR1, C5AR, C5R1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, CD antigen CD88,CD88, also known as C5a receptor (C5aR), is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.,C5a anaphylatoxin chemotactic receptor
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分子量
- observerd band 45kDa
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基因ID
- 728
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UniProt
- P21730
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途径
- Complement System
抗原
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