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COL2 抗体

This 小鼠 单克隆 anti-COL2 antibody (Clone 7F9) specifically detects COL2 in IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7212410
发货至: 中国
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Quick Overview for COL2 抗体 (ABIN7212410)

抗原

See all COL2 抗体
COL2 (Collagen, Type II (COL2))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

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  • 15
  • 10
  • 7
小鼠

克隆类型

  • 61
  • 15
单克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This COL2 antibody is un-conjugated

应用范围

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  • 8
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  • 2
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

7F9
  • 原理

    Collagen II Mouse Monoclonal Antibody (7F9)

    特异性

    The antibody detects endogenous Collagen II protein .

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Synthetic Peptide of Collagen II

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    COL2 (Collagen, Type II (COL2))

    别名

    Collagen II

    背景

    Mouse Anti-Collagen II Mouse Monoclonal Antibody (7F9),Collagen alpha-1(II) chain, Alpha-1 type II collagen,COL2A1 (collagen type II alpha 1 chain) encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1.,Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain, Chondrocalcin]

    分子量

    observerd band 142kDa

    基因ID

    1280

    UniProt

    P02458
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