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F13B 抗体 (AA 30-110)

This 兔 多克隆 anti-F13B antibody specifically detects F13B in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7220416
发货至: 中国
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Quick Overview for F13B 抗体 (AA 30-110) (ABIN7220416)

抗原

See all F13B 抗体
F13B (Coagulation Factor 13, B Polypeptide (F13B))

适用

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宿主

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克隆类型

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多克隆

标记

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This F13B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 30-110

    原理

    Factor XIII B Polyclonal Antibody

    特异性

    Factor XIII B Polyclonal Antibody detects endogenous levels of Factor XIII B protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human Factor XIII B at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    F13B (Coagulation Factor 13, B Polypeptide (F13B))

    别名

    Factor XIII B

    背景

    Rabbit Anti-Factor XIII B Polyclonal Antibody,F13B, Coagulation factor XIII B chain, Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain,F13B encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits, and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.,Coagulation factor XIII B chain

    分子量

    observerd band 80kDa

    基因ID

    2165

    UniProt

    P05160
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