F13B 抗体 (Middle Region)
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- 抗原 See all F13B 抗体
- F13B (Coagulation Factor 13, B Polypeptide (F13B))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This F13B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LRLIENGYFH PVKQTYEEGD VVQFFCHENY YLSGSDLIQC YNFGWYPESP
- 预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against F13B. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human F13B
- Top Product
- Discover our top product F13B Primary Antibody
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anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 151-179), (N-Term) antibody
F13B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41555 unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (Internal Region) antibodyF13B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (N-Term) antibodyF13B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) antibodyF13B 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 21-208) antibodyF13B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 260-403) antibodyF13B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 216-265) antibodyF13B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 61-110) antibodyF13B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 661 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- F13B (Coagulation Factor 13, B Polypeptide (F13B))
- 别名
- F13B (F13B 产品)
- 别名
- F13B antibody, coagulation factor XIII B chain antibody, LOC100347263 antibody
- 背景
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F13B contains 10 Sushi (CCP/SCR) domains. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Defects in F13B can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits, and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FXIIIB
Protein Interaction Partner: FGG, F13A1,
Protein Size: 661 - 分子量
- 73 kDa
- 基因ID
- 2165
- NCBI登录号
- NM_001994, NP_001985
- UniProt
- P05160
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