CHAC1 抗体
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北京 101111
Quick Overview for CHAC1 抗体 (ABIN7227870)
抗原
See all CHAC1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-CHAC1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CHAC1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human CHAC1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
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别名
- CHAC1
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背景
- Glutathione-specific gamma-glutamylcyclotransferase 1, Gamma-GCG 1, Blocks Notch protein, Botch, Cation transport regulator-like protein 1CHAC1 encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of CHAC1 may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.
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分子量
- 24kD
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基因ID
- 79094
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UniProt
- Q9BUX1
抗原
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