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CHAC1 抗体

The 兔 多克隆 anti-CHAC1 antibody (ABIN7227870) specifically detects CHAC1 in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7227870
发货至: 中国
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Quick Overview for CHAC1 抗体 (ABIN7227870)

抗原

See all CHAC1 抗体
CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))

适用

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  • 1
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人, 大鼠, 小鼠

宿主

  • 37
  • 9

克隆类型

  • 36
  • 10
多克隆

标记

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  • 1
  • 1
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This CHAC1 antibody is un-conjugated

应用范围

  • 30
  • 14
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  • 7
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Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-CHAC1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CHAC1 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human CHAC1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))

    别名

    CHAC1

    背景

    Glutathione-specific gamma-glutamylcyclotransferase 1, Gamma-GCG 1, Blocks Notch protein, Botch, Cation transport regulator-like protein 1CHAC1 encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of CHAC1 may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.

    分子量

    24kD

    基因ID

    79094

    UniProt

    Q9BUX1
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