CEP57 抗体 (AA 210-290)
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Quick Overview for CEP57 抗体 (AA 210-290) (ABIN7226070)
抗原
See all CEP57 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-290
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原理
- CEP57 Polyclonal Antibody
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特异性
- CEP57 Polyclonal Antibody detects endogenous levels of CEP57 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CEP57 at AA range: 210-290
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亚型
- IgG
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anti-Centrosomal Protein 57kDa (CEP57) antibody
CEP57 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-240) antibodyCEP57 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (Internal Region) antibodyCEP57 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-500) antibodyCEP57 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-500) antibodyCEP57 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 19-128) antibodyCEP57 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 1-240) antibodyCEP57 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) antibodyCEP57 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 19-128) antibodyCEP57 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Centrosomal Protein 57kDa (CEP57) (AA 241-290) antibodyCEP57 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CEP57 (Centrosomal Protein 57kDa (CEP57))
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别名
- CEP57
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背景
- Rabbit Anti-CEP57 Polyclonal Antibody,CEP57, KIAA0092, TSP57, Centrosomal protein of 57 kDa, Cep57, FGF2-interacting protein, Testis-specific protein 57, Translokin,CEP57 (centrosomal protein 57) encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in CEP57 cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,Centrosomal protein of 57 kDa
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分子量
- observerd band 50kDa
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基因ID
- 9702
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UniProt
- Q86XR8
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途径
- M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
抗原
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