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CEP57 抗体

CEP57 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7252420
发货至: 中国
  • 抗原 See all CEP57 抗体
    CEP57 (Centrosomal Protein 57kDa (CEP57))
    适用
    • 44
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 4
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEP57 antibody is un-conjugated
    应用范围
    • 28
    • 24
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Full length fusion protein
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CEP57 (Centrosomal Protein 57kDa (CEP57))
    别名
    CEP57 (CEP57 产品)
    别名
    3110002L15RIK antibody, CEP57 antibody, cep57r antibody, xCep57 antibody, c6orf182 antibody, 3110002l15rik antibody, RGD1309884 antibody, 3110002L15Rik antibody, 4921510P06Rik antibody, 4931428M20Rik antibody, AI467480 antibody, Tsp57 antibody, mKIAA0092 antibody, MVA2 antibody, PIG8 antibody, TSP57 antibody, centrosomal protein 57 antibody, centrosomal protein 57kDa-like 1 antibody, CEP57 antibody, cep57l1 antibody, Cep57 antibody
    背景
    This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 57 kDa

    UniProt
    Q86XR8
    途径
    M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
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